Sequence Information & Evolution
- Biological information:
- Molecular evolution and Population genetics:
- Mutations
- Transition probability matrix; approach to steady state
- Population size
- Genetic drift
- Selection
- Forward and backward Kolmogorov equations
- Gene annotation and similarity detection:
-
BLAST and database searches
- Scoring similarities
- Substitution matrices PAM, BLOSUM, …
-
Ungapped alignments
- Gapped alignments
- dynamic programming (transfer matrix)
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