Calendar

WEEK # TOPICS KEY DATES
1 Introduction
2 The Discovery of RNA Interference
3 The Basic Mechanism of RNAi
4 Physiological Relevance of the RNAi Pathway
5 Short-interfering RNAs (siRNAs) and their Delivery to Cells
6 Stable Expression of siRNA: Short Hairpins and Expression Vectors
7 Generation of Transgenic Animals for in vivo Silencing
8 Field Trip to Mouse-transgenesis Facility Assignment 1 due
9 Discussion of First Written Assignment Choose journal article papers for second assignment
10 Design of Potent siRNA Sequences
11 Large-scale Genetic Analyses Using RNAi
12 Student Oral Presentations of their Chosen Papers Assignment 2 due
13 Using RNAi in the Prevention of Disease
14 Course Summary and Discussion on the Future of RNAi