Subcellular Organization


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Video Clips

Video RealVideo®
8:10 minutes (19:47 - 27:57)

Eukaryotic animal cell organelles; focus on the nucleus and the mitochondrion. Prokaryotic cell organelles; comparison with eukaryotic cell organelles. Eukaryotic plant cell structures and organelles; focus on ribosomes and cell walls.

Instructors: Prof. Eric Lander, Prof. Robert Weinberg, Dr. Claudette Gardel
Prior Knowledge: None
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Video RealVideo®
8:13 minutes (27:57 - 36:10)

Detailed description on the endoplasmic reticulum (rough versus smooth), mitochondrion, nucleus, chromatin, plasma membrane, and cytoskeleton (microtubules and microfilaments).

Instructors: Prof. Eric Lander, Prof. Robert Weinberg, Dr. Claudette Gardel
Prior Knowledge: None
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Video RealVideo®
3:06 minutes (23:32 - 26:38)

Description and examples of level of multicellular organism-organs, tissues, single cells, organelles, and molecules.

Instructors: Prof. Penny Chisholm, Prof. Graham Walker, Dr. Julia Khodor, Dr. Michelle Mischke
Prior Knowledge: None
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Audio Clips

Audio RealAudio®
3:45 minutes (0:15 - 4:00)

Role of three dimensional structures in the function of various organs and systems. Cell movement builds structure.

Instructors: Prof. Tyler Jacks, Prof. Hazel Sive
Prior Knowledge: None
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Audio RealAudio®
7:25 minutes (4:00 - 11:25)

Epithelial cell sheets and single mesenchyme cells as the building block for the organism. Epithelial mesenchymal transition occurs during development to help cells adhere or move.

Instructors: Prof. Tyler Jacks, Prof. Hazel Sive
Prior Knowledge: None
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Audio RealAudio®
5:40 minutes (11:25 - 17:05)

Various types of junctions and cell surface adhesion molecules that are responsible for keeping cells together. Homotypic binding: randomly mixed cells spontaneously sort by type.

Instructors: Prof. Tyler Jacks, Prof. Hazel Sive
Prior Knowledge: None
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Audio RealAudio®
3:55 minutes (17:05 - 21:00)

Proteins and carbohydrates form the extracellular matrix. Functions to support the cells and for signal transduction.

Instructors: Prof. Tyler Jacks, Prof. Hazel Sive
Prior Knowledge: None
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Audio RealAudio®
1:11 minutes (21:00 - 22:11)

Cytoskeleton is responsible for shape and movement. Proteins that build the cytoskeleton: actin, tubulin.

Instructors: Prof. Tyler Jacks, Prof. Hazel Sive
Prior Knowledge: None
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Practice Problems

Document PDF#
Problem 1B (page 2)

Functions and characteristics of organelles.

Instructors: Prof. Eric Lander, Prof. Robert Weinberg, Dr. Claudette Gardel
Prior Knowledge: None
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Cell Adhesion (7.013, Spring 2005)

Document PDF
Problem 2a (page 3)

Adhesion of two types of cells and factors influencing adhesion.

Instructors: Prof. Tyler Jacks, Prof. Hazel Sive
Prior Knowledge: None
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Document PDF
All problems (All pages)

Name and function of organelles in prokaryotic and eukaryotic cells.

Instructors: Prof. Eric Lander, Prof. Robert Weinberg, Dr. Claudette Gardel
Prior Knowledge: None
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